Product ID:4-AMINOANTIPYRINE FREE BASE, A4383
MSDS Date:07/01/1999
FSC:6505
NIIN:00N092676
Status Code:A
MSDS Number: CJVPN

Emergency Phone: 314-771-5765

Info Phone: 314-771-5765

Cage: 21076

Telephone: 314-771-5765

Cage: 21076

4-AMINOANTIPYRINE (FREE BASE)

CAS: 83-07-8

RTECS: CD2480000

OSHA PEL N/K

ACGIH TLV: N/K

LD50 LC50 Mixture:SEE TOXICOLOGICAL INFORMATION.
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: HARMFUL IF SWALLOWED. MAY BE
HARMFUL IF INHALED. MAY BE HARMFUL IF ABSORBED THROUGH THE SKIN.
CAUSES EYE AND SKIN IRRITATION. MATERIAL IS IRRITATING TO MUCOUS
MEMBRANES AND UPPER RESPIRATORY TR ACT. TO THE BEST OF
MANUFACTURER'S KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND TOXICOLOGICAL
PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:EYES: IMMEDIATELY FLUSH WITH COPIOUS AMOUNTS OF WATER FOR AT
LEAST 15 MINUTES. SKIN: IMMEDIATELY WASH WITH SOAP AND COPIOUS
AMOUNTS OF WATER. INHALATION: REMOVE TO FRESH AIR. IF NOT
BREATHING, GIVE AR TIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT,
GIVE OXYGEN. INGESTION: WASH OUT MOUTH WITH WATER PROVIDED PERSON
IS CONSCIOUS. CALL A PHYSICIAN. WASH CONTAMINATED CLOTHING BEFORE
REUSE.

Extinguishing Media:WATER SPRAY, CARBON DIOXIDE, DRY CHEMICAL POWDER OR
APPROPRIATE FOAM.
Fire Fighting Procedures:WEAR NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS AND FULL PROTECTIVE EQUIPMENT .
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

Spill Release Procedures:WEAR NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS, RUBBER BOOTS AND HEAVY RUBBER GLOVES. SWEEP UP, PLACE IN
A BAG AND HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST. VENTILATE
AREA AND WASH SPILL SI TE AFTER MATERIAL PICKUP IS COMPLETE.

Handling and Storage Precautions:AVOID INHALATION. DO NOT GET IN EYES,
ON SKIN, ON CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE.
IRRITANT. KEEP TIGHTLY CLOSED. STORE IN A COOL DRY PLACE.

Respiratory Protection:NIOSH APPROVED RESPIRATOR.
Ventilation:MECHANICAL EXHAUST REQUIRED.
Protective Gloves:RUBBER GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EMERGENCY EYEWASH AND DELUGE
SHOWER .
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health

Melt/Freeze Pt:>108.C, 226.4F
M.P/F.P Text:108C - 110C
Appearance and Odor:YELLOW CRYSTALLINE POWDER.

STRONG OXIDIZING AGENTS, STRONG ACIDS, ACID CHLORIDES, ACID ANHYDRIDES.
Hazardous Decomposition Products:TOXIC FUMES OF CARBON MONOXIDE, CARBON
DIOXIDE, NITROGEN OXIDES.

Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE
SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL
ENVIRONMENTAL REGULATIONS.

Toxicological Information:RTECS NUMBER: DC2480000 - ANTIPYRINE,
4-AMINO-. TOXICITY DATA: ORL-RAT LD50: 1700 MG/KG; BCFAAI 117, 638,
1978. IPR-RAT LD50: 1200 MG/KG; JPETAB 99, 171, 1950. ORL-MUS LD50:
800 MG/KG; CCCCAK 47, 636, 1982. IPR-MUS LD50: 270 MG/KG; ARZNAD
10, 820, 1960. TARGET ORGAN DATA: BEHAVIORAL (CONVULSIONS OR EFFECT
ON SEIZURE THRESHOLD, EXCITEMENT). ONLY SELECTED REGISTRY OF TOXIC
EFFECTS OF CHEMICAL SUBSTA NCES (RTECS) DATA IS PRESENTED HERE. SEE
ACTUAL ENTRY IN RTECS FOR COMPLETE INFORMATION.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:DATA NOT YET AVAILABLE.

Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
INFORMATION.

Federal Regulatory Information:EUROPEAN INFORMATION: HARMFUL. R 22:
HARMFUL IF SWALLOWED. R 36/37/38: IRRITATING TO EYES, RESPIRATORY
SYSTEM AND SKIN. S 26: IN CASE OF CONTACT WITH EYES, RINSE
IMMEDIATELY WITH PLENTY OF WATER AND S EEK MEDICAL ADVICE. S 36:
WEAR SUITABLE PROTECTIVE CLOTHING. REVIEWS, STANDARDS, AND
REGULATIONS: OEL=MAK. NOHS 1974: HZD 82277; NIS 4; TNF 114; NOS 3;
TNE 1130. NOES 1983: HZD 82277; NIS 5; TNF 1080; NOS 7; TNE 12808;
TFE 9012. EPA GENETOX PROGRAM 1988, NEGATIVE: HYSTIDINE
REVERSION-AMES TEST. EPA TSCA SECTION 8 (B) CHEMICAL INVENTORY.
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, DECEMBER 1998.
State Regulatory Information: